Abstract— Calopogunium mucunoides are forage leguminous plants that grows annually or perennially. The leaves of Calopogunium mucunoides are used for the management of ulcer. Gas chromatography-mass spectrometry method was used in the characterization of Calopogunium mucunoides. The extract was prepared using soxhlet extraction method and concentrated at 40ºC in an oven. The concentrated extract was analyzed using GC-MS analysis. The gas chromatogram showed the presence of twelve compounds. The suggested compounds are histamine (1.60%), 2-ethyl-2-hexen-1-al (2.45%), methenamine (1.86%), 9,12,15-octadecatrien-1-ol (6.26%), methyl 14-methylpentadecanoate (8.01%), hexadecanoic acid (6.18%), hexadecanoic acid, ethylester (9.13%), 9,12-octadecadienoic acid, methylester (34.98%), 2-ethylhex-3-enal (16.13%), 1H-Indol-5-ol (2.73%), p-methoxybenzoic acid, octylester (3.97%), gamolenic acid (6.70%). Bioactivity studies showed that Calopogunium mucunoides is an acidifier, acidulant, histamine-Inhibitor, oligosaccharide provider, catechol-o-methyl-transferase-inhibitor, inhibitor of uric acid production, antidote (heavy metals) and previtamin-A provider. We hereby recommend the isolation and synthesis of these bioactive compounds for drug development.
Keywords— Calopogunium mucunoides, gas chromatography, mass spectrometry, phytocompounds, ethanol, retention time PDF